Nabilone safe and effective in pain reduction in combination with gabapentin compared to placebo

Study Type:Therapy

OE Level Evidence:2

Journal Level of Evidence:N/A

Nabilone as an adjunctive to gabapentin for multiple sclerosis-induced neuropathic pain: a randomized controlled trial

Pain Med. 2015 Jan;16(1):149-59. doi: 10.1111/pme.12569

Contributing Authors: D Turcotte M Doupe M Torabi A Gomori K Ethans F Esfahani K Galloway M Namaka

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Synopsis

Current convention in managing neuropathic pain (NPP) from relapsing-remitting multiple sclerosis (RRMS) often involves gabapentin (GBP) as first-line therapy and cannabis (CB) as an alternative, had other therapies not worked. The combination of GBP and CB has not been explored. In this study, 15 patients with NPP from RRMS and still experience considerable pain after a stable dosage of GBP were ...