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Nabilone 1mg per day safe and effective in treating chronic upper motor neuron syndrome

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Ace Report Cover
September 2018

Nabilone 1mg per day safe and effective in treating chronic upper motor neuron syndrome

Vol: 7| Issue: 9| Number:11| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : a double-blind placebo-controlled cross-over trial

J Neurol. 2006 Oct;253(10):1337-41

Contributing Authors:
J Wissel T Haydn J Mller C Brenneis T Berger W Poewe LD Schelosky

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Synopsis

13 patients with spasticity-associated pain caused by chronic upper motor neuron syndrome (UMNS) received nabilone or placebo for 4-week periods in random order with a 1-week washout period. 11 patients completed the study and were analyzed. Significant improvement in pain was found with nabilone 1mg per day compared to the placebo. No significant improvements were found for spasticity, motor func...

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