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Author Verified
Meta-analysis
ACE Report #10242
Ace Report Cover General Orthopaedics

VitD supplementation, with or without calcium, does not reduce fracture rate in community adults


Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A

Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Fractures in Community-Dwelling Adults: Evidence Report and Systematic Review for the US Preventive Services Task Force

JAMA. 2018 Apr 17;319(15):1600-1612

Contributing Authors: LC Kahwati RP Weber H Pan M Gourlay E LeBlanc M Coker-Schwimmer M Viswanathan

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Synopsis

A total of 8 randomized controlled trials were included for data on efficacy, and 9 randomized controlled trials were included for data on harms, in this meta-analysis which investigated the effects of vitamin D and/or calcium supplementation in community-dwelling adults over the age of 50 years. Overall, quantitative and qualitative assessment of fractures rates from efficacy studies demonstrated...

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