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ACE Report #10142
Ace Report Cover Trauma

AAOS2018: TXA effective in operative management for high-energy pelvic and femoral fractures

Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Use of Tranexamic Acid in High-Energy Fractures of the Pelvis and Femur

Contributing Authors: D Kiner R Swafford PJ Nowotarski CA Spitler E Row WE Gardner MJ Hankins

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


84 patients with a high-energy fracture of the pelvis or femur and scheduled for open reduction and internal fixation were randomized to perioperative intravenous tranexamic acid (TXA) or no tranexamic acid (control). Patients were assessed for calculated total blood loss, transfusion rate, number of units transfused, postoperative drop in hematocrit, and incidence of venous thromboembolic complic...

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