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RCT
ACE Report #10037
Ace Report Cover General Orthopaedics

OTS povidone-iodine vs. PI-based skin and nasal antiseptic vs. placebo in orthopaedic surgery


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Povidone-Iodine-Based Solutions for Decolonization of Nasal Staphylococcus aureus: A Randomized, Prospective, Placebo-Controlled Study

J Arthroplasty. 2017 Sep;32(9):2815-2819

Contributing Authors: J Parvizi RM Tabatabaee AF Chen MG Maltenfort T Nicholson M Rezapoor

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Synopsis

429 patients scheduled for major orthopaedic surgery were randomized to nasal decolonization with either an off-the-shelf povidone-iodine solution, a specialized Skin and Nasal Antiseptic povidone-iodine solution (3M), or placebo saline swabs. Patients were assessed for Staphylococcus aureus (S. aureus) colonization of the nares. Nasal S. aureus colonization rate was assessed at 4 hours and 24 hou...

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