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IV & topical TXA similarly safe & effective for reducing blood loss and transfusion in TKA
January 2017
IV & topical TXA similarly safe & effective for reducing blood loss and transfusion in TKA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
A randomized comparative study of topical versus intravenous tranexamic acid administration in enhanced recovery after surgery (ERAS) total knee replacement
J Orthop. 2016 Mar 26;13(3):127-31Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
90 patients scheduled for total knee arthroplasty were randomized to one of three groups; one group was administered 1g of tranexamic acid intravenously; one group was administered 1g of tranexamic acid topically; one group underwent surgery without tranexamic acid administration. Calculated blood loss, the incidence of transfusion, and complications, which included venous thromboembolic events we...
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