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No significant difference in effect on cartilage volume between HA vs placebo injection
January 2016
No significant difference in effect on cartilage volume between HA vs placebo injection
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Determination of Cartilage Volume Using MRI in Patients with Knee Osteoarthritis: Efficacy Study of 25 Milligrams of Sodium Hyaluronate (2.5 Ml) Versus Placebo
Clin Exp Pharmacol 2012, 2:2Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
60 females with mild to moderate knee osteoarthritis were randomized to receive either weekly intra-articular injections of a placebo or hyaluronic acid (GoOn) for 5 weeks. The purpose of the study was to evaluate the effects of hyaluronic acid injection over 6 months on MRI-assessed cartilage volume. The results indicated that the hyaluronic acid did not confer a significant effect on cartilage v...
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