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Efficacy and safety of a single, 6mL Hylan G-F 20 injection in knee OA treatment
January 2016
Efficacy and safety of a single, 6mL Hylan G-F 20 injection in knee OA treatment
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Single, intra-articular treatment with 6 ml hylan G-F 20 in patients with symptomatic primary osteoarthritis of the knee: a randomised, multicentre, double-blind, placebo controlled trial
Ann Rheum Dis. 2010 Jan;69(1):113-9Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
253 patients with primary knee osteoarthritis (OA) were randomized to receive a single intra-articular injection of either 6mL Hylan G-F 20 or saline placebo. The purpose of the study was to assess the efficacy of Hylan G-F 20 at reducing pain and improving knee function, as well as to assess the safety of its use. The primary outcome of interest was pain at 26 weeks after injection, as measured b...
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