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Oral salmon calcitonin reduces bone and cartilage degradation markers in patients with OA

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Ace Report Cover
March 2013

Oral salmon calcitonin reduces bone and cartilage degradation markers in patients with OA

Vol: 2| Issue: 2| Number:213| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

The effect of oral salmon calcitonin delivered with 5-CNAC on bone and cartilage degradation in osteoarthritic patients: a 14-day randomized study

Osteoarthritis Cartilage. 2010 Feb;18(2):150-9. Epub 2009 Sep 1.

Contributing Authors:
MA Karsdal I Byrjalsen K Henriksen BJ Riis EM Lau M Arnold C Christiansen

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Synopsis

73 patients, aged 57-75 years of age, with painful OA being experienced in at least one knee, were randomly placed into 3 groups to test the pharmacokinetic and pharmacodynamic effect of oral salmon calcitonin (sCT). Two of the groups received varying dosages of oral sCT (0.6 mg vs. 0.8) while the third group received a placebo. Results demonstrated that patients who received oral sCT had lower bo...

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