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Perineural Dexamethasone Prolongs Analgesia After PENG Block in Elderly Hip Arthroplasty
November 2025
Perineural Dexamethasone Prolongs Analgesia After PENG Block in Elderly Hip Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Perineural dexamethasone effectively prolongs anaesthesic block duration in total hip arthroplasty, reduces opioid consumption, and does not compromise motor function, nerve integrity, or glycaemic control.
Int Orthop . 2025 Aug;49(8):1791-1799.Synopsis
Sixty six patients aged ≥65 years undergoing total hip arthroplasty (THA) were randomized to receive a pericapsular nerve group (PENG) block with 20 mL 0.2% ropivacaine (n=33) or the same PENG block plus 4 mg perineural dexamethasone (n=33). The primary outcome was time to first rescue opioid. Secondary outcomes included 48-h opioid consumption (morphine milliequivalents), NRS pain at 4/6/12/24 h,...
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