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Transcranial Direct Current Stimulation Primed Aquatic Training for Knee Osteoarthritis
November 2025
Transcranial Direct Current Stimulation Primed Aquatic Training for Knee Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The impacts of transcranial direct current stimulation combined with aquatic neuromuscular training on pain, function, kinesiophobia, knee instability, and quality of life in knee osteoarthritis: a double-blind randomized trial.
J Neuroeng Rehabil . 2025 Jul 5;22(1):151.Synopsis
Forty-four women with knee osteoarthritis were randomized to receive anodal transcranial direct current stimulation (tDCS) (2 mA, M1, 20 min) followed by aquatic neuromuscular training (ANMT) (n=22) or sham tDCS plus the same ANMT (n=22); at six weeks, analyses included twenty per group. The primary outcome was pain (0–10 NRS) assessed weekly and at six weeks. Secondary outcomes were physical func...
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