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Efficacy and Safety of a Novel Low-Dose Water-Dispersible Turmeric Extract in the Management of KOA
November 2025
Efficacy and Safety of a Novel Low-Dose Water-Dispersible Turmeric Extract in the Management of KOA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Efficacy and Safety of a Novel Low-Dose Water-Dispersible Turmeric Extract in the Management of Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
J Pain Res . 2025 Jan 25:18:411-427.Synopsis
One hundred and fourty patients with mild-to-moderate knee osteoarthritis were randomized per-protocol to receive WDTE60N 250 mg once daily (n = 70) or matching placebo (n = 70). The primary outcome was change in 100-mm VAS pain from baseline to Day 90. Secondary outcomes included VAS at interim time points; KOOS subscales (Pain, Symptoms, ADL, Sport/Rec, QoL); serum hsCRP, TNF-α, IL-6, IL-1β at D...
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