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Pain Mechanisms & Psychosocial Variables in Patients With Chronic Pain After Total Knee Arthroplasty
November 2025
Pain Mechanisms & Psychosocial Variables in Patients With Chronic Pain After Total Knee Arthroplasty
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Pain Mechanisms and Psychosocial Variables in Patients With Chronic Pain After Total Knee Arthroplasty: Secondary Analysis From a Randomised Controlled Trial.
Eur J Pain . 2025 Jul;29(6):e70064.Synopsis
Sixty-nine patients with chronic post-TKA pain were randomized to neuromuscular exercise+pain neuroscience education (PNE) (n=36) or PNE alone (n=33). The primary outcome of interest for this secondary analysis was temporal summation of pain (TSP) at the index knee. Secondary outcomes included TSP extra-segmentally, pressure pain thresholds (PPT) locally and extra-segmentally, conditioned pain mod...
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