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Pre-op IV Ferric Carboxymaltose Reduces Mortality and Transfusion Needs After Hip-Fracture Surgery
November 2025
Pre-op IV Ferric Carboxymaltose Reduces Mortality and Transfusion Needs After Hip-Fracture Surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
The Effect of Preoperative Intravenous Iron Supplementation on Mortality and Blood Transfusion Requirements in Elderly Patients Undergoing Hip Fracture Surgery: A Prospective Randomized Controlled Trial.
J Clin Med . 2025 Jul 3;14(13):4713.Synopsis
Two hundred and twenty patients with geriatric hip fractures were randomized to receive either preoperative IV ferric carboxymaltose 1000 mg ~12 h before surgery (n=110) or no iron (n=110), with all patients managed using a restrictive transfusion threshold (primarily Hb <8 g/dL or symptomatic). The primary outcome was all-cause mortality at 6 and 12 months. Secondary outcomes included perioperati...
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