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Adipose-Derived MSCs vs Triamcinolone for Knee Osteoarthritis
October 2025
Adipose-Derived MSCs vs Triamcinolone for Knee Osteoarthritis
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Effects of Ultrasound-Guided Corticosteroid Injection Compared to Mesenchymal Stem Cell Injection in Patients With Grade II and III Knee Osteoarthritis: A Randomized Double-Blind Controlled Trial.
Am J Phys Med Rehabil . 2025 Jul 1;104(7):646-653.Synopsis
Sixty patients with grade II–III knee osteoarthritis were randomized to receive adipose-derived mesenchymal stem cells (MSCs) (n=30) or triamcinolone (n=30). Primary outcome: pain (VAS). Secondary outcomes: WOMAC subscales (stiffness, pain, physical function), knee ROM, and MRI parameters. Outcomes were assessed at baseline, 2, 4, and 24 weeks. Overall, pain trajectories differed by group with a b...
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