Early Hyperbaric Oxygen Therapy Reduces Muscle Injury and Inflammation After Total Knee Arthroplasty
Early Hyperbaric Oxygen Therapy Reduces Muscle Injury and Inflammation After Total Knee Arthroplasty
Effect of hyperbaric oxygen therapy on postoperative muscle damage and inflammation following total knee arthroplasty: a randomized controlled trial.
Sci Rep. 2025 Jul 1;15:22039.Synopsis
Eighty patients with primary knee osteoarthritis scheduled for unilateral TKA were randomized to receive hyperbaric oxygen therapy (HBOT) added to standard care (n=40) or normobaric oxygen therapy (n=40). The primary outcome was serum muscle-injury biomarkers (CK, Mb, LDH, GOT). Secondary outcomes included IL-6, CRP, VAS pain (rest/motion), knee ROM, quadriceps strength, swelling ratio, and HSS sc...
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