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Methylprednisolone and Tranexamic Acid Use in Total Hip Arthroplasty for Accelerated Recovery
June 2025
Methylprednisolone and Tranexamic Acid Use in Total Hip Arthroplasty for Accelerated Recovery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Clinical utilization of methylprednisolone in conjunction with tranexamic acid for accelerated rehabilitation in total hip arthroplasty.
J Orthop Surg Res. 2023 Oct 4;18(1):747.Synopsis
Eighty patients undergoing primary total hip arthroplasty were randomized to receive either tranexamic acid alone (n=40) or tranexamic acid combined with methylprednisolone (n=40). The primary outcomes were levels of CRP and IL-6 as markers of inflammation. Secondary outcomes included pain (VAS scores), use of analgesics, nausea and vomiting (PONV), blood glucose fluctuations, fatigue (ICFS), rang...
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