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Efficacy & Safety of Flurbiprofen Cataplasms vs. Loxoprofen Sodium Cataplasms in Knee Osteoarthritis

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Ace Report Cover
February 2025

Efficacy & Safety of Flurbiprofen Cataplasms vs. Loxoprofen Sodium Cataplasms in Knee Osteoarthritis

Vol: 307| Issue: 2| Number:87| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1

Efficacy and safety of flurbiprofen cataplasms versus loxoprofen sodium cataplasms in knee osteoarthritis: a randomized controlled trial.

Chin Med J (Engl) . 2023 Sep 20;136(18):2187-2194.

Contributing Authors:
D Li Y Cheng P Yuan Z Wu J Liu J Kan K Zhang Z Wang H Zhang G Zhang T Xue J Jia S Zhai Z Guan

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Synopsis

Two hundred fifty patients with knee osteoarthritis were randomized to receive either flurbiprofen cataplasms (FPC) (n=124) or loxoprofen sodium cataplasms (LSC) (n=125) for 28 days. The primary outcome of interest was the change in pain intensity measured by the visual analog scale (VAS) from baseline to day 28. Secondary outcomes included the extent of pain relief, changes in joint function asse...

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