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Favourable pain relief, less opioid-related AEs with LIA vs. intrathecal morphine after TKR surgery

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Ace Report Cover
August 2019

Favourable pain relief, less opioid-related AEs with LIA vs. intrathecal morphine after TKR surgery

Vol: 8| Issue: 8| Number:15| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

A comparison of the analgesic efficacy of local infiltration analgesia vs. intrathecal morphine after total knee replacement: A randomised controlled trial

Eur J Anaesthesiol. 2019 Apr;36(4):264-271.

Contributing Authors:
G Iohom G Shorten D McCarthy J McNamara J Galbraith F Loughnane

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Synopsis

53 patients scheduled for a unilateral total knee replacement under spinal anesthesia were randomized to receive local infiltration analgesia with levobupivacaine and adrenaline, or intrathecal preservative-free morphine in conjunction with the spinal anesthesia. The primary outcomes of interest were pain scores at 24 hours at rest and on passive flexion to 30deg, measured on a Visual Analog Scale...

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