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Musculoskeletal Evidence
ACE Reports.
Osteoarthritis
The efficacy of metformin for pain, function, and quality of life in knee osteoarthritis: A systematic review and meta-analysis.
Semin Arthritis Rheum. 2026 01-Apr;():. 10.1016/j.semarthrit.2025.152908
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
The efficacy of metformin for pain, function, and quality of life in knee osteoarthritis: A systematic review and meta-analysis.
Semin Arthritis Rheum. 2026 01-Apr;():. 10.1016/j.semarthrit.2025.152908
Peri-Operative
Esketamine infusion for the prevention of tourniquet-induced intra-operative hypertension during below-knee orthopaedic surgery: a randomised controlled trial.
Anaesthesia. 2026 01-Jan;():. 10.1111/anae.70027
Esketamine infusion for the prevention of tourniquet-induced intra-operative hypertension during below-knee orthopaedic surgery: a randomised controlled trial.
Anaesthesia. 2026 01-Jan;():. 10.1111/anae.70027
Arthroplasty
Reduced Ropivacaine Volume with Perineural Dexamethasone in PENG Block for Total Hip Arthroplasty: A Randomized Controlled Trial.
J Clin Med. 2025 01-Dec;():. 10.3390/jcm14248722
Reduced Ropivacaine Volume with Perineural Dexamethasone in PENG Block for Total Hip Arthroplasty: A Randomized Controlled Trial.
J Clin Med. 2025 01-Dec;():. 10.3390/jcm14248722
Peri-Operative
Effectiveness of pericapsular nerve group block for hip fracture pain management in the emergency department: results of the ED-PENG-B randomised controlled trial.
BMC Emerg Med. 2025 01-Nov;():. 10.1186/s12873-025-01401-x
Effectiveness of pericapsular nerve group block for hip fracture pain management in the emergency department: results of the ED-PENG-B randomised controlled trial.
BMC Emerg Med. 2025 01-Nov;():. 10.1186/s12873-025-01401-x
Peri-Operative
Efficacy and Safety of Tranexamic Acid Combined with Absorbable Hemostat in Reducing Perioperative Blood Loss in Total Knee Arthroplasty: A Prospective, Blinded, Randomized Controlled Trial.
J Bone Joint Surg Am. 2025 01-Oct;():. 10.2106/JBJS.24.01236
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
Efficacy and Safety of Tranexamic Acid Combined with Absorbable Hemostat in Reducing Perioperative Blood Loss in Total Knee Arthroplasty: A Prospective, Blinded, Randomized Controlled Trial.
J Bone Joint Surg Am. 2025 01-Oct;():. 10.2106/JBJS.24.01236
General Orthopaedics
Comparison of the postoperative analgesic efficacy of pericapsular nerve group block (PENG) and anterior quadratus lumborum block in hip fracture surgery: A prospective randomized study.
Sci Prog. 2025 01-Oct;():. 10.1177/00368504251382032
Comparison of the postoperative analgesic efficacy of pericapsular nerve group block (PENG) and anterior quadratus lumborum block in hip fracture surgery: A prospective randomized study.
Sci Prog. 2025 01-Oct;():. 10.1177/00368504251382032
Trauma
Intramedullary administration of tranexamic acid reduces bleeding in proximal femoral nail antirotation surgery for intertrochanteric fractures in elderly individuals: A randomized controlled trial.
Chin J Traumatol. 2025 01-May;():. 10.1016/j.cjtee.2024.01.006
Intramedullary administration of tranexamic acid reduces bleeding in proximal femoral nail antirotation surgery for intertrochanteric fractures in elderly individuals: A randomized controlled trial.
Chin J Traumatol. 2025 01-May;():. 10.1016/j.cjtee.2024.01.006
Shoulder & Elbow
Preoperative Intravenous Carbazochrome Sodium Sulfonate Improves Visual Clarity in Patients Undergoing Arthroscopic Rotator Cuff Repair Compared to Tranexamic Acid and Sodium Chloride: A Randomized Controlled, Triple-Blinded, Prospective Study.
Arthroscopy. 2025 01-Aug;():. 10.1016/j.arthro.2025.01.051
Preoperative Intravenous Carbazochrome Sodium Sulfonate Improves Visual Clarity in Patients Undergoing Arthroscopic Rotator Cuff Repair Compared to Tranexamic Acid and Sodium Chloride: A Randomized Controlled, Triple-Blinded, Prospective Study.
Arthroscopy. 2025 01-Aug;():. 10.1016/j.arthro.2025.01.051
Arthroplasty
Pericapsular Nerve Group (PENG) Associated with Lateral Femoral Cutaneous Nerve (LFCN) Block Versus Fascia Iliaca Compartment Block (FICB) for Total Hip Replacement Surgery: Double-Blind Randomized Controlled Trial.
J Pers Med. 2025 01-Jun;():. 10.3390/jpm15060230
Pericapsular Nerve Group (PENG) Associated with Lateral Femoral Cutaneous Nerve (LFCN) Block Versus Fascia Iliaca Compartment Block (FICB) for Total Hip Replacement Surgery: Double-Blind Randomized Controlled Trial.
J Pers Med. 2025 01-Jun;():. 10.3390/jpm15060230
Peri-Operative
Pericapsular nerve group (PENG) block for early pain management of elderly patients with hip fracture: a single-center double-blind randomized controlled trial.
Reg Anesth Pain Med. 2023 01-Nov;():. 10.1136/rapm-2022-104117
Pericapsular nerve group (PENG) block for early pain management of elderly patients with hip fracture: a single-center double-blind randomized controlled trial.
Reg Anesth Pain Med. 2023 01-Nov;():. 10.1136/rapm-2022-104117
Osteoarthritis
Effects of whole-body vibration training as an adjunct to conventional rehabilitation exercise on pain, physical function and disability in knee osteoarthritis: A systematic review and meta-analysis.
PLoS One. 2025 01-Feb;():. 10.1371/journal.pone.0318635
Effects of whole-body vibration training as an adjunct to conventional rehabilitation exercise on pain, physical function and disability in knee osteoarthritis: A systematic review and meta-analysis.
PLoS One. 2025 01-Feb;():. 10.1371/journal.pone.0318635
Arthroplasty
Effect of Pericapsular Nerve Group Block with Wound Infiltration vs Modified Supra-Inguinal Fascia Iliaca Block on Postoperative Analgesia in Adult Patients Undergoing Total Hip Arthroplasty - A Randomized Clinical Trial.
J Pain Res. 2025 01-May;():. 10.2147/JPR.S517578
Effect of Pericapsular Nerve Group Block with Wound Infiltration vs Modified Supra-Inguinal Fascia Iliaca Block on Postoperative Analgesia in Adult Patients Undergoing Total Hip Arthroplasty - A Randomized Clinical Trial.
J Pain Res. 2025 01-May;():. 10.2147/JPR.S517578
Arthroplasty
Erector spinae plane block (ESPB) vs. pericapsular nerve group (PENG) block in total hip arthroplasty in elderly patients: a randomized, double-blinded, controlled trial.
Anaesthesiol Intensive Ther. 2025 01-May;():. 10.5114/ait/203170
Erector spinae plane block (ESPB) vs. pericapsular nerve group (PENG) block in total hip arthroplasty in elderly patients: a randomized, double-blinded, controlled trial.
Anaesthesiol Intensive Ther. 2025 01-May;():. 10.5114/ait/203170
Pediatric Orthopaedics
Pericapsular Nerve Group (PENG) Block Versus Lumbar Erector Spinae Plane Block (ESPB) in Pediatric Hip Surgery: A Randomized, Double-Blinded, Controlled Trial.
J Pediatr Orthop. 2025 01-Apr;():. 10.1097/BPO.0000000000002882
Pericapsular Nerve Group (PENG) Block Versus Lumbar Erector Spinae Plane Block (ESPB) in Pediatric Hip Surgery: A Randomized, Double-Blinded, Controlled Trial.
J Pediatr Orthop. 2025 01-Apr;():. 10.1097/BPO.0000000000002882
Arthroplasty
Randomized clinical trial comparing pericapsular nerve group (PENG) block and periarticular local anesthetic infiltration for total hip arthroplasty.
Reg Anesth Pain Med. 2023 01-Oct;():. 10.1136/rapm-2023-104332
Randomized clinical trial comparing pericapsular nerve group (PENG) block and periarticular local anesthetic infiltration for total hip arthroplasty.
Reg Anesth Pain Med. 2023 01-Oct;():. 10.1136/rapm-2023-104332
Peri-Operative
Effect of ultrasound-guided pericapsular nerve group (PENG) block on pain during patient positioning for central nervous blockade in hip surgery: a randomized controlled trial.
BMC Anesthesiol. 2023 01-Sep;():. 10.1186/s12871-023-02245-3
Effect of ultrasound-guided pericapsular nerve group (PENG) block on pain during patient positioning for central nervous blockade in hip surgery: a randomized controlled trial.
BMC Anesthesiol. 2023 01-Sep;():. 10.1186/s12871-023-02245-3
Peri-Operative
Functional recovery and pain control following Pericapsular Nerve Group (PENG) block following hip surgeries: a systematic review and meta-analysis of randomised controlled trials.
Arch Orthop Trauma Surg. 2025 01-Mar;():. 10.1007/s00402-025-05825-9
Functional recovery and pain control following Pericapsular Nerve Group (PENG) block following hip surgeries: a systematic review and meta-analysis of randomised controlled trials.
Arch Orthop Trauma Surg. 2025 01-Mar;():. 10.1007/s00402-025-05825-9
Arthroplasty
The PENG Block in Elective Primary Anterior Total Hip Arthroplasty Is Associated with Reduced Length of Stay: A Multidisciplinary Prospective Randomized Double-Blinded Controlled Trial.
J Bone Joint Surg Am. 2025 01-Apr;():. 10.2106/JBJS.24.00825
This study has been identified as potentially high impact.
OE's AI-driven High Impact metric estimates the influence a paper is likely to have by integrating signals from both the journal in which it is published and the scientific content of the article itself.
Developed using state-of-the-art natural language processing, the OE High Impact model more accurately predicts a study's future citation performance than journal impact factor alone.
This enables earlier recognition of clinically meaningful research and helps readers focus on articles most likely to shape future practice.
The PENG Block in Elective Primary Anterior Total Hip Arthroplasty Is Associated with Reduced Length of Stay: A Multidisciplinary Prospective Randomized Double-Blinded Controlled Trial.
J Bone Joint Surg Am. 2025 01-Apr;():. 10.2106/JBJS.24.00825
Arthroplasty
Comparison between pericapsular nerve group (PENG) block with lateral femoral cutaneous nerve block and supra-inguinal fascia iliaca compartment block (S-FICB) for total hip arthroplasty: a randomized controlled trial.
J Anesth. 2023 01-Aug;():. 10.1007/s00540-023-03192-6
Comparison between pericapsular nerve group (PENG) block with lateral femoral cutaneous nerve block and supra-inguinal fascia iliaca compartment block (S-FICB) for total hip arthroplasty: a randomized controlled trial.
J Anesth. 2023 01-Aug;():. 10.1007/s00540-023-03192-6
Arthroplasty
Effect of phenylephrine versus ephedrine on the incidence of postoperative delirium in olderly adults undergoing knee arthroplasty under general anesthesia: a single-center trial.
Sci Rep. 2024 01-Jul;():. 10.1038/s41598-024-68273-2
Effect of phenylephrine versus ephedrine on the incidence of postoperative delirium in olderly adults undergoing knee arthroplasty under general anesthesia: a single-center trial.
Sci Rep. 2024 01-Jul;():. 10.1038/s41598-024-68273-2
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