Orthopaedic Surgeon - Australia

So does that mean if an injection doesn’t help , a hip replacement won’t help either ?

Orthopaedic Surgeon - United States

100% agree the saline finding is surprising. May warrant a non blinded saline to blinded saline injection trial. What if there is value in dilution if proinflammatory cytokines and chemokines? Would this analysis conclude; by way of injection delineating articulations hip vs extrarticular pain (soft tissue or radiating pain) that the patient with a good response, who would therefore goes on to a successful total hip arthroplasty, is simply having a placebo effect from the surgery as well? Would like to see focused analysis of diagnostic injections before we abandon a procedure entirely.

Orthopaedic Surgeon - Canada

Arthritis of the hip is a complex problem, with multiple factors that can be contributing to pain and dysfunction. Outcome analysis based on pain scale is only one factor to consider, and direct efficacy of treatment should only be inferred from well designed RCT studies that are reproducible. While this research method is amazingly powerful, it’s clinical application requires further analysis.