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Synopsis: 90 patients with degenerative spinal disorders undergoing lumbar spinal fusion were randomized to receive either cognitive-behavioural therapy or standard treatment.The objective of this study was to determine whether or not cognitive-behavioural therapy (CBT) has the ability to affect early postoperative outcomes such as back pain, mobility, analgesic consumption, and hospital stay duration.Findings indicated no significant differences between groups for improvement in postoperative back pain, analgesic consumption, and length of hospitalization. However, mobility was... Read More »
Level 2 RCT
16%
Synopsis: One hundred patients scheduled for total knee arthroplasty under spinal anaesthesia and preoperative single-shot femoral nerve block were randomized to receive either continuous femoral nerve block with 0.125% bupivacaine for 48 hours after arrival to the postanaesthesia care unit, or to placebo saline.The purpose of this study was to evaluate the analgesic effect of continuous femoral nerve block as compared with placebo saline after total knee arthroplasty. Upon follow-up for... Read More »
Author verified Level 1 RCT
16%
Synopsis: 474 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were included in a 3-year, double-blind, RCT to evaluate the effect of vitamin D supplementation on the rate of radiographic disease progression.Compared to a placebo group, patients treated with vitamin D supplementation did not demonstrate a slower rate of joint space narrowing (JSN) on radiographs over the 3-year follow-up.There were also no significant differences between groups in pain, stiffness, or function. Read More »
Level 2 RCT
16%
Synopsis: The present study is a meta-analysis evaluating the efficacy of autologous whole blood (AWB) therapy versus corticosteroid injections in the treatment of epicondylopathy and plantar fasciopathy (PF).The primary outcome was pain relief at 2-6, 8-13, and 24-26 weeks.The authors included a total of 9 RCTs, and found statistically significant results in favour of corticosteroids at 2-6 weeks for patients with plantar fasciopathy, and in favour of AWB as early as 8 weeks up to 24 weeks for individuals with epicondylopathy. Read More »
Author verified Level 1 Meta Analysis
16%
Synopsis: 22 randomized controlled trials were included in this network meta-analysis, that included over 10 injectable treatments, to evaluate comparative efficacy for the management of plantar faciopathy.The primary outcome of this study was pain relief.At 0-2 month follow-up, micronized dehydrated human amniotic/chorionic membrane was the most likely treatment to be effective for pain relief.At 2-6 months, botulinum toxin A was the treatment most likely to be effective for pain relief, while a treatment most likely to be effective beyond 12 months could not be identified from the limited amount of evidence available at this time point.The lack of trials available was a limiting factor of this network meta-analysis, exemplified by the lack of studies reporting data on micronized dehydrated human amniotic/chorionic membrane beyond 2 months. Further trials are... Read More »
Level 1 Meta Analysis
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