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The preventative effects of conservative treatments on the MRI progression of knee OA

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Ace Report Cover
November 2016

The preventative effects of conservative treatments on the MRI progression of knee OA

Vol: 5| Issue: 11| Number:21| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Reducing progression of knee OA features assessed by MRI in overweight and obese women: secondary outcomes of a preventive RCT

Osteoarthritis Cartilage. 2016 Jun;24(6):982-90.

Contributing Authors:
ML Landsmeer J Runhaar P van der Plas M van Middelkoop D Vroegindeweij B Koes PJ Bindels EH Oei SM Bierma-Zeinstra

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Synopsis

This study was an extension of the Prevention of knee Osteoarthritis in Overweight Females (PROOF) trial. 407 females, between the ages of 50 and 60, at high risk of developing knee osteoarthritis (OA) were included. Patients were randomized using a 2x2 factorial design into 4 groups, that received either glucosamine sulfate (1500mg orally per day) and a tailored diet and exercise program, glucosa...

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