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Osteoporosis: Zoledronic acid increases bone mineral density and reduces fracture rate
August 2013
Osteoporosis: Zoledronic acid increases bone mineral density and reduces fracture rate
Study Type:Meta analysis
OE Level Evidence:2
Journal Level of Evidence:N/A
Efficacy of intravenous zoledronic acid in the prevention and treatment of osteoporosis: A meta-analysis
Asian Pac J Trop Med. 2012 Sep;5(9):743-8. doi: 10.1016/S1995-7645(12)60118-7Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
This meta-analysis included 9 studies comparing zoledronic acid and a placebo in patients with osteoporosis. Results from the analysis indicated that zoledronic acid was effective in increasing bone mineral density and reducing fracture rate. The zoledronic acid group also demonstrated a significantly lower rate of serious adverse events than the control group. According to subgroup analyses, olde...
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