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Dexmedetomidine inhibits lipid peroxidation in anticipated ischaemia-reperfusion injury
April 2013
Dexmedetomidine inhibits lipid peroxidation in anticipated ischaemia-reperfusion injury
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Dexmedetomidine reduces the ischemia-reperfusion injury markers during upper extremity surgery with tourniquet
J Hand Surg Am. 2008 Jul-Aug;33(6):941-7.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
40 patients (ASA Grade 1 to 2) scheduled to undergo hand and forearm surgery with tourniquet and brachial plexus anesthesia via axillary approach for upper-limb block were randomized to receive a continuous infusion of dexmedetomidine or saline as placebo until the end of surgery. Following evaluations over a 2 week period, results exhibited that the dexmedetomidine treatment led to a significant ...
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