AAOS 2016: TXA vs. epsilon-aminocaproic acid provide comparable outcomes after TKA

Similar efficacy with EACA and TXA for reduction of blood loss in patients undergoing TKA

J Orthop Traumatol. 2019 Jul 18;20(1):28.

AAOS2019: TXA vs. EACA vs. control on pain and function in an ACL reconstruction

IV and Intra-Articular TXA vs. Epsilon-Aminocaproic Acid in Primary Total Knee Arthroplasty

Orthop Surg. 2023 01-Mar;():. 10.1111/os.13638

Antifibrinolytic agents in the setting of scoliosis surgery found to reduce blood loss

PLoS One. 2015 Sep 18;10(9):e0137886.

AAOS: IV tranexamic acid & aminocaproic acid on reducing blood loss in orthopaedic surgery

Similar Clinical Outcomes in Oral TXA vs Epsilon-Aminocaproic Acid Up to 30 Days After THA Surgery

Blood Coagul Fibrinolysis. 2021 01-Mar;():. 10.1097/MBC.0000000000001005

IV tranexamic acid reduces blood loss and transfusion rate in primary THA

Orthopedics. 2016 Sep 1;39(5):e883-92

Intravenous and topical tranexamic acid have similar efficacy in TKA

Arch Orthop Trauma Surg. 2015 Apr;135(4):573-88.

IA-TXA effective compared to placebo for blood loss and transfusion reduction in TKA

J Knee Surg. 2018 Jan;31(1):56-67

Antifibrinolytic agents reduce blood loss and transfusion requirements in spine surgery

PLoS One. 2013 Nov 22;8(11):e82063

Blood loss and transfusion needs reduced with TXA in major orthopaedic surgery

J Surg Res. 2014 Jan;186(1):318-27. doi: 10.1016/j.jss.2013.08.020. Epub 2013 Sep 13

Similar reduction in total blood loss with intravenous/articular TXA administration in TKA

Arch Orthop Trauma Surg. 2015 Apr;135(4):573-88.

TXA efficacy in perioperative spinal surgery bleeding

Spine J. 2015 Apr 1;15(4):752-761.

Oral ibandronic acid inferior to IV zoledronic acid for metastatic breast cancer to bone

Lancet Oncol. 2014 Jan;15(1):114-22. doi: 10.1016/S1470-2045(13)70539-4.

Tranexamic acid reduces blood transfusion requirements during surgery

BMJ. 2012 May 17;344:e3054. doi: 10.1136/bmj.e3054

Tranexamic acid is effective in reducing blood loss, while maintaining safety, in THA

Arch Orthop Trauma Surg. 2013 Jul;133(7):1017-27. doi: 10.1007/s00402-013-1761-2. Epub 2013 Apr 25

Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA

Clin Orthop Relat Res. 2011 Oct;469(10):2874-80. Epub 2011 Apr 22

AAOS 2016: Interim evaluation of tranexamic acid vs placebo in acetabular fracture surgery

TKA: Topical Fibrin Spray and Tranexamic acid reduce blood loss

J Bone Joint Surg Br. 2007 Mar;89(3):306-9