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Examining the effects of hyaluronic acid versus placebo in patients with bilateral knee OA
January 2016
Examining the effects of hyaluronic acid versus placebo in patients with bilateral knee OA
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Intra-articular hyaluronic acid in osteoarthritis of the knee: an investigation into mechanisms of action
Osteoarthritis Cartilage. 1994 Jun;2(2):133-40.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
12 women with bilateral knee osteoarthritis (24 affected knees) were each randomized to have one knee receive intra-articular injections of hyaluronic acid, and to have their other knee receive saline placebo injections. The purpose of the study was to examine the mechanisms of action for hyaluronic acid treatment in treating knee osteoarthritis, as measured over 9 weeks. Outcomes of interest incl...
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