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Orthokin effective in improving KOOS symptoms and KOOS sport scores in knee osteoarthritis

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Ace Report Cover
March 2013

Orthokin effective in improving KOOS symptoms and KOOS sport scores in knee osteoarthritis

Vol: 2| Issue: 2| Number:194| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared to placebo in a prospective randomized controlled trial

Osteoarthritis Cartilage. 2008 Apr;16(4):498-505. Epub 2007 Sep 6.

Contributing Authors:
K G Auw Yang N J H Raijmakers E R A van Arkel J J Caron P C Rijk W J Willems JAC Zijl A J Verbout Dhert Saris

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Synopsis

167 patients (>18 yr old) with severe symptomatic knee osteoarthritis (OA) were randomized to receive 6 intrarticular injections of either Orthokin or saline, as placebo, over a 3 week period. The purpose of this study was to compare improvement in pain and function between injection therapies. At 12 months, Orthokin-treated patients consistently showed higher improvement than placebo-treated pati...

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