Showing 13 - 24 of 422 reports matching: Spine
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Synopsis: 40 patients with single-level degenerative lumbar disc disease who were scheduled for transforaminal lumbar interbody fusion (TLIF) were randomized to undergo the procedure with or without the use of navigation technology. The purpose of this study was to compare perioperative outcomes, including incision length, intraoperative blood loss, operative time, postoperative blood loss, time to mobilization, and the length of hospital stay between groups, as well as the clinical outcomes at 3-month and 2-year follow-up. Significant differences in Read More »
Level 2 RCT
Synopsis: 70 patients with low back pain and a directional preference observed during a mechanical assessment were randomized to treatment using the McKenzie method or motor control exercises. The purpose of this study was to compare the effects that these two treatments had on the recruitment of the transversus abdominis, obliquus internus, and obliquus externus muscles, as well as their effects on pain intensity, functional outcome, and global perceived effect. Outcomes were reported Read More »
Author verified Level 2 RCT
Synopsis: 80 patients with ankylosing spondylitis were randomized to receive a Chinese patent medicine, 0.6g Kunxian, or a placebo drug, 3 times daily for 12 weeks. The purpose of this study was to determine the efficacy of Kunxian, measured using the Assessment of SpondyloArthritis international Society (ASAS) 20 response rate. Other outcomes included Read More »
Level 2 RCT
Synopsis: 115 patients with vertebral compression fractures were randomized to undergo either kyphoplasty or vertebroplasty. The purpose of this study was to compare the efficacy of the two treatments in terms of pain and disability using the numeric rating scale and the Roland-Morris Disability Questionnaire. Outcomes were assessed Read More »
Author verified Level 2 RCT
Synopsis: 40 patients with adolescent idiopathic scoliosis were randomized to have a computer-aided design and manufactured thoraco-lumbo-sacral orthosis with or without the addition of finite element simulation during the design process. Patients underwent radiographic evaluation during brace wearing to assess correction in thoracic and lumbar Cobb angle, as well as thoracic kyphosis and lumbar lordosis angles. Results demonstrated a Read More »
Level 2 RCT
Synopsis: 90 patients with degenerative spinal disorders undergoing lumbar spinal fusion were randomized to receive either cognitive-behavioural therapy or standard treatment. The objective of this study was to determine whether or not cognitive-behavioural therapy (CBT) has the ability to affect early postoperative outcomes such as back pain, mobility, analgesic consumption, and hospital stay duration. Findings indicated no Read More »
Level 2 RCT
Synopsis: 107 patients with single-level cervical spondylosis were randomized to undergo either cervical disc arthroplasty (CDA) with the Mobi-C Cervical Disc Prosthesis or ACDF. The purpose of this study was to compare patient-reported outcome measures, the radiographic range of motion of the index segment, and subsequent surgery rates between groups. At 5 year Read More »
Level 2 RCT
Synopsis: 40 patients with low back pain due to sacroiliac joint arthritis were randomized to receive a singular steroid/anesthetic injection with the aid of either ultrasound or fluoroscopic guidance. The purpose of this study was to compare differences in efficacy (pain, disability), accuracy (intraarticular vs. periarticular needle placements), and patient discomfort/satisfaction throughout three-month follow-up. Results demonstrated that Read More »
Level 2 RCT
Synopsis: 389 patients with moderate-to-severe chronic low back pain (LBP) were randomized to receive one of five dose-ranging subcutaneous injection treatments: 1mg fulranumab every 4 weeks, 3mg fulranumab every 4 weeks, 3mg fulranumab every 4 weeks after a 6mg loading dose, 10mg fulranumab every 4 weeks, or placebo every 4 weeks. The purpose of this study was to determine the efficacy and safety of fulranumab compared to placebo in terms of the LBP numeric rating scale for pain intensity, Oswestry Disability Index scores, Brief Pain Inventory pain intensity and interference scores and treatment relief, and patient global assessment scores. Outcomes were measured Read More »
Level 2 RCT
Synopsis: 97 patients scheduled for posterior lumbar interbody fusion were randomized to postoperative analgesia through one of three groups: pregabalin 75mg, pregabalin 150mg, or diazepam 5mg as an active placebo. The purpose of this study was to determine the analgesic efficacy of the two pregabalin doses. Pain scores and Read More »
Level 2 RCT
Synopsis: 12 randomized controlled trials were included in this meta-analysis for the purpose of investigating potential differences in reoperation rates following anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) at the index level and/or adjacent levels for patients with cervical spondylosis. Results demonstrated that patients who underwent CDA required significantly fewer reoperations at the index level, the adjacent levels, or at either level type when compared to patients who received ACDF up to seven years post-surgery. However, due to Read More »
Level 1 Meta Analysis
Synopsis: 90 patients with thoracolumbar fractures were randomized to receive one of three surgical interventions: three-level percutaneous fixation, two-level percutaneous fixation, or three-level open fixation. The purpose of this study was to compare clinical and radiological outcomes of these three procedures after a mean follow-up of 17.7 months. Results demonstrated comparable Read More »
Level 2 RCT