Related ACE Reports
- Published: Mar 2017
- ACE Report #9585
AAOS 2017: Health-related QOL and function deficit remains at 12-month in open fracture pa
Study Type: Randomized Trial
OE Level of Evidence: N/A
Journal Level of Evidence: N/A
CONFERENCE ACE REPORTS
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Why was this study needed now?
Few trials have provided data on the health-related quality of life and function of patients with open fractures managed operatively, and if outcomes vary by the method of lavage used to clean the wound.
What was the principal research question?
In patients with open fractures who were managed surgically, were there significant differences in health-related quality-of-life and functional outcomes between lavage with soap or saline? Additionally, how did health-related quality-of-life and functional outcomes change over a one-year period?
|Population:||2,447 patients with open wound fractures. Patients were included in 2X3 factorial design using varying irrigation solution and irrigation pressures.|
|Intervention:||Soap Irrigation: Patients underwent soap irrigation. Patients were randomized within this group to 1 of three pressures (very low, low, or high)|
|Comparison:||Saline irrigation: Patients underwent saline irrigation. Patients were randomized within this group to 1 of three pressure (very low, low, high)|
|Outcomes:||Health-related quality-of-life (HR-QoL) and functional outcomes were assessed using both mental and physical components of the Short-Form 12-Item Health Survey (MCID = 5pts) and the EuroQol-5 Dimensions (EQ-5D) (MCID = 0.03).|
|Methods:||RCT: 2x3 factorial design|
|Time:||Outcomes were evaluated preoperatively, at 2 and 6 weeks, and at 3, 6, 9, and 12 months.|
What were the important findings?
What should I remember most?
How will this affect the care of my patients?
The authors responsible for this critical appraisal and ACE Report indicate no potential conflicts of interest relating to the content in the original publication.