AAOS2017: Mensical allograft transplantation versus tailored physiotherapy

Study Type: Randomized Trial
OE Level of Evidence: N/A
Journal Level of Evidence: N/A
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
36 patients with symptomatic recurrence after partial meniscectomy were included in this pilot randomized controlled trial and parallel preference study. 21 patients were randomized to either meniscal allograft transplantation or a physiotherapy program, while 15 patients chose their group as part of a preference study. Baseline demographics and treatment outcomes were similar between the randomized and non-randomized cohorts, which allowed for the data to be pooled and analyzed together. Patients were followed Please login to view the rest of this report. Please login to view the rest of this report.
Why was this study needed now?
Meniscal allograft transplantation procedures are often performed in young patients with meniscal deficient compartments of the knee. While these procedures have been performed for over 30 years, no high-quality trials have been conducted to verify meniscal allograft transplantation's efficacy.
What was the principal research question?
In the management of recurrent symptoms following partial meniscectomy, are there significant differences between meniscal allograft transplantation and a tailored physiotherapy program in patient-report outcome measures and cartilage volume loss on MRI when assessed over a 12-month follow-up period?
Population: 36 patients with a symptomatic knee compartment following previous partial meniscectomy. A total of 21 patients agreed to randomization, while 15 elected to choose their treatment.
Intervention: Meniscal allograft transplantation: Participants underwent meniscal allograft transplantation
Comparison: Physiotherapy: Patients took part in a personalized physiotherapy program.
Outcomes: Clinical scores included the Knee Injury and Osteoarthritis Outcome Score (KOOS), the International Knee Documentation Committee (IKDC) score, and the Lysholm score. MRI was performed to assess cartilage volume.
Methods: RCT; Pilot Study, Single-center. As treatment outcomes were reported to not differ between randomized and non-randomized cohorts, data analysis was performed including all patients based on received treatment.
Time: Follow-up scheduled for 4, 8 and 12 months post-intervention.
What were the important findings?
What should I remember most?
How will this affect the care of my patients?
The authors responsible for this critical appraisal and ACE Report indicate no potential conflicts of interest relating to the content in the original publication.