Related ACE Reports
- Published: Mar 2017
- ACE Report #9604
AAOS2017: NSAID does not impair pediatric long bone fracture healing
Study Type: Randomized Trial
OE Level of Evidence: N/A
Journal Level of Evidence: N/A
CONFERENCE ACE REPORTS
This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.
Why was this study needed now?
Various analgesic drugs are used for pain management following fracture. Specifically in children and adolescents, despite the common use of non-steroidal anti-inflammatory drugs (NSAIDs), no previous high-quality studies have examined the safety of theses agents related to fracture healing.
What was the principal research question?
In analgesia post-long bone fracture in pediatric patients, is there any significant difference in fracture healing between ibuprofen (NSAID) and acetaminophen?
|Population:||81 patients, 16 years of age or younger, with a fracture of a long bone. All patients were given oxycodone for the management of breakthrough pain.|
|Intervention:||Ibuprofen group: Patients were administered ibuprofen as part of their post-fracture analgesia regimen.|
|Comparison:||Acetaminophen (control) group: Patients were administered acetaminophen as part of their post-fracture analgesia regimen.|
|Outcomes:||Outcome measures included fracture healing, and pain on a visual analog scale (VAS),|
|Time:||Follow-up intervals included 1-3 days, 1-2 weeks, 6 weeks, 10-12 weeks, and 6 months after injury.|
What were the important findings?
What should I remember most?
How will this affect the care of my patients?
The authors responsible for this critical appraisal and ACE Report indicate no potential conflicts of interest relating to the content in the original publication.