Showing 1 - 12 of 39 reports matching: Viscosupplementation
Journals
Specialties
Date of Publication
to
Synopsis: 240 patients aged 40-75 with knee osteoarthritis (OA) were randomized to receive 5 weekly injections of hyaluronan, or to receive 5 placebo injections. The purpose of the study was to determine the effects of hyaluronan injection on OA symptoms and knee function, up to 20 weeks after the start of treatment. Primary outcomes of Read More »
Level 2 RCT
Synopsis: 39 patients with primary knee osteoarthritis were randomized to receive either 9 hyaluronan injections over the course of a year, or to a control group which received no injections. The purpose of the study was to assess the clinical and structure-modifying properties of hyaluronan injection treatment, using arthroscopy to view physical changes at the joint. The primary outcome Read More »
Level 2 RCT
Synopsis: 246 patients age 60 or older with knee osteoarthritis were randomized to 1 of 3 groups: one group received three intra-articular injections of Artzal hyaluronan, one group received three intra-articular injections of Synvisc hyaluronan, and one group received three intra-articular injections of placebo. The primary outcomes of interest were weight-bearing pain 26 weeks after treatment, and the percentage of patients reporting positive outcomes 1 year after treatment. Other outcomes of Read More »
Level 2 RCT
Synopsis: 67 patients with knee osteoarthritis (OA) scheduled for arthroscopic debridement were randomized to treatment with or without subsequent, postoperative intra-articular injections of hyaluronic acid (HA) injections. The purpose of the study was to evaluate any possible effect of postoperative HA injections on knee pain and functional disability over 24-week follow-up. Outcomes were assessed Read More »
Level 2 RCT
Synopsis: 91 patients with knee osteoarthritis were randomized to receive either 5 weekly intra-articular injections of hyaluronan, or to receive 5 placebo intra-articular injections. The purpose of the study was to determine the clinical effects of hyaluronan injection therapy, in terms of its efficacy and safety. Outcomes included VAS Read More »
Level 2 RCT
Synopsis: 80 patients undergoing arthroscopic joint lavage for knee osteoarthritis were randomized to either receive instillation of hyaluronic acid (HA) solution following arthroscopy, or to receive no HA treatment. The primary outcomes of interest were VAS pain scores recorded by both patient and the study investigator. Secondary outcomes included Read More »
Level 2 RCT
Synopsis: 110 patients with knee osteoarthritis and effusion were randomized to receive either 4 weekly intra-articular injections of hyalectin, or 4 weekly injections of saline solution. The purpose of the study was to determine the efficacy of hyalectin treatment in terms of effusion reduction, pain, and function, and to identify any safety risks, up to one year after treatment. The primary outcome Read More »
Level 2 RCT
Synopsis: 30 elderly patients with confirmed diagnosis of mild to moderate osteoarthritis of the knee were randomized to receive either 3 weekly injections of hyaluronic acid or a placebo treatment. The purpose of the study was to evaluate if intra-articular hyaluronic acid injections significantly increased self-selected and fast gait velocity compared to placebo. Follow-up was conducted Read More »
Level 1 RCT
Synopsis: 20 patients undergoing arthroscopic treatment with lavage for knee osteoarthritis were randomized to either receive 3 hyaluronic acid (HA) injections starting 2 weeks after arthroscopy or to receive no hyaluronic acid treatment. The purpose of the study was to determine if HA injection provided additional benefits to pain reduction when used in conjunction with arthroscopic treatment. Outcomes included VAS Read More »
Level 2 RCT
Synopsis: 253 patients with primary knee osteoarthritis (OA) were randomized to receive a single intra-articular injection of either 6mL Hylan G-F 20 or saline placebo. The purpose of the study was to assess the efficacy of Hylan G-F 20 at reducing pain and improving knee function, as well as to assess the safety of its use. The primary outcome Read More »
Author verified Level 2 RCT
Synopsis: 100 participants with knee osteoarthritis and joint effusion were randomized into one of 5 groups. The purpose of the study was to evaluate and compare clinical results of three different dosing schedules - 1, 3, or 5 weekly injections - of intra-articualr hyaluronic acid, to that of placebo treatment and control arthrocentesis. Outcomes of interest Read More »
Level 2 RCT
Synopsis: 80 patients with knee osteoarthritis were randomized to one of two treatment groups (a group receiving 2 intra-articular hylan injections vs. a group receiving 3 intra-articular hylan injections) or to one of two control groups (a group receiving 2 placebo injections or a group receiving 3 placebo injections). The purpose of the study was to assess the safety and efficacy of hylan injection therapy, and to compare the differences in injection schedules (2 or 3 injections). Outcomes included rate Read More »
Level 2 RCT