Showing 1 - 12 of 85 reports matching: PRP
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Synopsis: 79 elderly patients with femoral neck or trochanteric hip fractures were randomized to a group receiving protein-rich supplementation and weekly bisphosphonates, weekly bisphosphonates alone, or a control group; all three groups received calcium and vitamin D supplementation. The purpose of this randomized controlled trial was to compare these treatments in terms of their effect on body composition, hand-grip strength, and quality of life. The results displayed Read More »
Level 2 RCT
Synopsis: 80 patients with grade I or II hamstring injury were randomized to receive two injections of either platelet-rich plasma (PRP) or placebo. The purpose of this study was to compare time to return to sport between groups, as well as evaluate subjective and clinical outcome measures between groups over 26 weeks post-injury and re-injury rate over the first year of follow-up. Results demonstrated no Read More »
Level 1 RCT
Synopsis: 93 patients with early-stage osteoarthritis (OA) of the knee were randomized to receive either a single cycle of platelet-rich plasma (PRP) treatment consisting of 3 injections, or to receive the same treatment plus an additional second cycle, repeated 1 year later. Patients were followed-up for a minimum of 2 years after initiation of treatment. The purpose of Read More »
Author verified Level 2 RCT
Synopsis: 40 patients undergoing micro-fracture surgery for osteochondral lesions (OCLs) of the talus were randomized to 1 of 3 injection therapy groups: the platelet-rich plasma (PRP) group, hyaluronic acid (HA) group, or control group, who received a saline injection. The purpose of the study was to observe and compare the effects of PRP and HA on patient pain and recovery. Outcomes included the Read More »
Level 2 RCT
Synopsis: Fifty eight patients with osteoarthritis (OA) were randomized to receive arthroscopic treatment with or without intra-operative leukocyte-poor platelet-rich plasma (LP-PRP) injection. The goal of this study was to determine if there were any benefits to the added PRP intervention in terms of pain, function, or quality of life. The primary outcome Read More »
Author verified Level 2 RCT
Synopsis: 30 patients with lateral epicondylitis (LE) persisting for a period of more than 6 months and no bilateral involvement were randomly assigned to receive treatment with an injection of either platelet-rich plasma (PRP) or methylprednisolone, a corticosteroid (CS). Both treatments were compared in terms of functional outcomes and ultrasonographic findings involving morphological and vascularization changes observed in the common extensor tendon, when assessed up to 6 months post treatment. The study found Read More »
Level 2 RCT
Synopsis: 38 patients with rotator cuff tear were randomized to undergo arthroscopic rotator cuff repair either with or without platelet-rich plasma (PRP) injections. The purpose of the study was to determine if PRP treatment accelerated recovery and increased stability of the repaired rotator cuff, at a minimum of 16 months post-surgery. Results showed that Read More »
Conference Report
Synopsis: 8 randomized controlled trials were included in this meta-analysis evaluating the efficacy of platelet-rich plasma on patients undergoing arthroscopic full-thickness rotator cuff repair. Rate of retear, incidence of complications and functional outcomes, including pain, strength and range of motion were assessed. The results of Read More »
Author verified Level 1 Meta Analysis
Synopsis: 25 patients with a rotator cuff tear <3cm, undergoing arthroscopic repair were randomized to one of two groups; a platelet rich plasma (PRP) group, which received intraoperative application of PRP along the repair site and a PRP injection at 4 weeks postoperatively, or a control group which received saline in a similar manner. Patients were followed up at 2, 4, and 6 weeks after surgery for pain, general and condition-specific quality of life, and disability. There were no Read More »
Level 1 RCT
Synopsis: 160 patients with knee osteoarthritis were randomized to receive platelet-rich plasma injections or hyaluronic acid injections. This was done to assess the effects of each treatment on clinical outcomes and patient quality of life over a 52-week period. Quality of life Read More »
Author verified Level 2 RCT
Synopsis: 8 studies were included in this systematic review examining whether platelet-rich plasma (PRP) injections are an effective treatment for chronic plantar fasciopathy (PF). While 2 of the studies indicated no significant improvement when platelet-rich plasma injections were administered compared to either corticosteroids (CCS) injections or dextrose prolotherapy, the other 6 studies indicated that PRP may be an effective intervention based mainly on VAS and Roles and Maudsley scores. No complications were Read More »
Author verified Level 3 Meta Analysis
Synopsis: 75 patients with complete supraspinatus tears were randomized to undergo arthroscopic rotator cuff repair with or without the injection of platelet-rich plasma (PRP). The purpose of this study was to compare functional and structural results between groups up to 24 months post-surgery. The UCLA score Read More »
Author verified Level 2 RCT