Showing 1 - 12 of 4355 reports matching:
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Synopsis: 77 patients with symptomatic, Kellgren-Lawrence grade II-IV knee osteoarthritis were randomized to intraarticular hyaluronic acid (IAHA) injections with or without an additional, single periarticular lidocaine-corticosteroid injection (PALCI) at the beginning of treatment. The purpose of this study was to determine if the addition of PALCI to IAHA had a significant effect on pain after 1, 3, 6, 12, 26 and 52 weeks. Visual analog pain Read More »
Level 2 RCT
Synopsis: 90 patients presenting to the emergency department with moderate to severe pain due to mild or moderate blunt trauma were randomized to be managed with either intranasal (IN) ketamine, intravenous (IV) morphine, or intramuscular (IM) morphine. Patients were assessed for pain every 5 minutes for the first 60 minutes after administration. Results demonstrated significant Read More »
Level 2 RCT
Synopsis: The present study is a meta-analysis evaluating the efficacy of autologous whole blood (AWB) therapy versus corticosteroid injections in the treatment of epicondylopathy and plantar fasciopathy (PF). The primary outcome was pain relief at 2-6, 8-13, and 24-26 weeks. The authors included Read More »
Level 1 Meta Analysis
Synopsis: 50 patients scheduled for posterior pedicle screw fixation of a thoracolumbar fracture were randomized to surgical wound injection of methylene blue or saline. The purpose of this study was to compare postoperative pain and disability between groups at 48 hours postoperatively and at 2- and 6-month follow-up. Results demonstrated significantly Read More »
Level 2 RCT
Synopsis: 26 patients scheduled for opening-wedge high tibial osteotomy were randomized to grafting with a dehydrated equine wedge with or without augmentation with a nanohydroxyapatite paste. The purpose of this study was to assess and compare graft integration between groups on CT over a 12-month follow-up. Results suggested better Read More »
Level 2 RCT
Synopsis: 222 patients with OARSI grades 1-3 knee osteoarthritis were randomized to intra-articular viscosupplementation with either an intermediate-molecular-weight hyaluronic acid plus mannitol, an antioxidant, (HAnOX-M), or high-molecular-weight hyaluronic acid (Bio-HA). The purpose of this study was to evaluate if the HAnOX-M group demonstrated non-inferior results on Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain and Function sub-scores compared to the Bio-HA group over 26-week follow-up. Results suggested non-inferiority Read More »
Level 2 RCT
Synopsis: 74 patients with plantar fasciitis were randomized to treatment with either extracorporeal shockwave therapy (ESWT) or botulinum toxin type A (BoNT-A) injections. The purpose of this study was to compare pain on a visual analog scale (VAS), Roles and Maudsley pain scores, plantar fasciitis thickness on ultrasound, and the incidence of adverse events. Patients were followed-up Read More »
Author verified Level 2 RCT
Synopsis: Eleven randomized controlled trials (n=1048 patients) were included in this meta-analysis for the purpose of comparing percutaneous vertebroplasty (PVP) and conservative therapy treatment for patients with osteoporotic vertebral compression fractures (OVCFs). The primary outcome of interest was pain severity at three follow-up ranges: 1 to 2 weeks, 2 to 3 months, and at 1 year. Results demonstrated that Read More »
Level 1 Meta Analysis
Synopsis: 32 patients with a thoracolumbar fracture were randomized to receive either percutaneous short-segmental pedicle screw fixation with intermediate screws or percutaneous bilateral pedicle screw fixation without intermediate screws. The purpose of this study was to compare the two techniques in terms of operative time, estimated blood loss, postoperative back pain and function, sagittal Cobb angle, vertebrae body index, anterior vertebrae body height, and complications. Outcomes were assessed Read More »
Level 2 RCT
Synopsis: 474 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were included in a 3-year, double-blind, RCT to evaluate the effect of vitamin D supplementation on the rate of radiographic disease progression. Compared to a placebo group, patients treated with vitamin D supplementation did not demonstrate a slower rate of joint space narrowing (JSN) on radiographs over the 3-year follow-up. There were also Read More »
Level 2 RCT
Synopsis: 80 patients with moderate to severe acromioclavicular joint dislocation scheduled for coracoclavicular ligament reconstruction were randomized to either triple Endobutton fixation or double Endobutton fixation. The purpose of this study was to determine if triple Endobutton fixation was beneficial over double Endobutton fixation with respect to surgical outcomes, patient-reported functional outcomes, and radiographic outcomes over a minimum 12-month follow-up. Results demonstrated no Read More »
Level 2 RCT
Synopsis: 30 patients with osteoporotic vertebral compression fractures were randomized to undergo percutaneous vertebral cement augmentation with either SpineJack or kyphoplasty (Kyphx Xpander balloon). The purpose of this study was to compare the clinical, radiographic, and safety outcomes of these two techniques. Outcomes were assessed Read More »
Level 2 RCT