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Combined IV-topical TXA more effective than IV TXA alone in total hip and knee arthroplasty
August 2017
Combined IV-topical TXA more effective than IV TXA alone in total hip and knee arthroplasty
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A
Combined intravenous and topical tranexamic acid versus intravenous use alone in primary total knee and hip arthroplasty: A meta-analysis of randomized controlled trials
Int J Surg. 2016 Dec;36(Pt A):324-329Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Five randomized controlled trials were included in this meta-analysis investigating the efficacy and safety of combined intravenous-intraarticular tranexamic acid administration to that of intravenous tranexamic acid alone. Pooled results demonstrated significantly lower total blood loss, smaller postoperative hemoglobin drop, and lower incidence of transfusion in combined intravenous-intraarticul...
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