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Vitamin D does not improve radiological or clinical outcomes for patients with knee OA

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Ace Report Cover
April 2017

Vitamin D does not improve radiological or clinical outcomes for patients with knee OA

Vol: 6| Issue: 4| Number:37| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:N/A

The effect of vitamin D supplementation on knee osteoarthritis, the VIDEO study: a randomised controlled trial

Osteoarthritis Cartilage. 2016 Nov;24(11):1858-1866

Contributing Authors:
NK Arden S Cro S Sheard CJ Doré A Bara SA Tebbs DJ Hunter S James C Cooper TW O'Neill A Macgregor F Birrell R Keen

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Synopsis

474 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were included in a 3-year, double-blind, RCT to evaluate the effect of vitamin D supplementation on the rate of radiographic disease progression. Compared to a placebo group, patients treated with vitamin D supplementation did not demonstrate a slower rate of joint space narrowing (JSN) on radiographs over the 3-year follow-up. T...

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