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TKA: liposomal bupivacaine vs. standard periarticular injection in chronic opioid users

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Ace Report Cover
November 2016

TKA: liposomal bupivacaine vs. standard periarticular injection in chronic opioid users

Vol: 5| Issue: 11| Number:46| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Is There a Benefit for Liposomal Bupivacaine Compared to a Traditional Periarticular Injection in Total Knee Arthroplasty Patients With a History of Chronic Opioid Use?

J Arthroplasty. 2016 Aug;31(8):1702-5

Contributing Authors:
R Schwarzkopf M Drexler MW Ma VM Schultz KT Le TF Rutenberg JB Rinehart

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Synopsis

38 patients with a history of chronic opioid use who were scheduled for primary total knee arthroplasty were randomized to periarticular injection analgesia containing either liposomal bupivacaine, or a standard drug mixture of ropivacaine, a non-steroidal anti-inflammatory drug (Toradol), and epinephrine. The purpose of this study was to evaluate if liposomal bupivacaine offered significantly low...

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