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Greater efficacy of 15mg/kg TXA versus 10mg/kg TXA in total hip arthroplasty
August 2016
Greater efficacy of 15mg/kg TXA versus 10mg/kg TXA in total hip arthroplasty
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Single-dose tranexamic acid for reducing bleeding and transfusions in total hip arthroplasty: A double-blind, randomized controlled trial of different doses
Thromb Res. 2016 May;141:119-23Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
124 patients scheduled for total hip arthroplasty were randomized to one of three groups: a single intravenous dose of 10mg/kg tranexamic acid (TXA); a single intravenous dose of 15mg/kg TXA; or a single intravenous dose of placebo saline. The purpose of this study was to examine and compare efficacy and safety outcomes between groups. While both TXA groups demonstrated a significant reduction in ...
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