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Leukocyte-poor PRP effective and safe versus placebo for symptomatic knee OA treatment
July 2016
Leukocyte-poor PRP effective and safe versus placebo for symptomatic knee OA treatment
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Intra-articular Autologous Conditioned Plasma Injections Provide Safe and Efficacious Treatment for Knee Osteoarthritis: An FDA-Sanctioned, Randomized, Double-blind, Placebo-controlled Clinical Trial
Am J Sports Med. 2016 Apr;44(4):884-91Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
30 patients with Kellgren-Lawrence grade II-III knee osteoarthritis were randomized to receive three weekly intra-articular injections of either leukocyte-poor platelet rich plasma (LP-PRP) autologous conditioned plasma or placebo saline. The purpose of this study was to determine if LP-PRP administration demonstrated efficacy for improvement in pain, stiffness, and function on the Western Ontario...
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