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WCO-IOF 2016: Odanacatib has a significant effect on volumetric BMD versus placebo

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Ace Report Cover
May 2016

WCO-IOF 2016: Odanacatib has a significant effect on volumetric BMD versus placebo

Vol: 5| Issue: 5| Number:17| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Effect of odanacatib on bone mineral density and estimated bone strength in postmenopausal women: a CT-based substudy of the phase 3 long-term odanacatib fracture trial (LOFT)

Contributing Authors:
K Engelke B Langdahl T DeVilliers TM Keaveny H Genant S Ather H Giezek A Lombardi A Leung A de Papp

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

A subset of 164 women from the Long-Term Odanacatib Fracture Trial were included in this imaging sub-study to evaluate the effect of odanacatib versus placebo on volumetric bone mineral density (vBMD) of the lumbar spine and total hip. Follow-up was made at 24 months of treatment, and percent change in trabecular vBMD of the lumbar spine and cortical vBMD of total hip were compared. Results demons...

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