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G-CSF based PBSC transplantation with biomechanical support is safe & effective in ONFH
July 2016
G-CSF based PBSC transplantation with biomechanical support is safe & effective in ONFH
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Combination treatment of biomechanical support and targeted intra-arterial infusion of peripheral blood stem cells mobilized by granulocyte-colony stimulating factor for the osteonecrosis of the femoral head: a randomized controlled clinical trial
J Bone Miner Res. 2015 Apr;30(4):647-56Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
55 patients (89 hips) with osteonecrosis of the femoral head (ONFH) were randomized into 2 groups with either a porous tantalum rod implantation and granulocyte-colony stimulating factor (G-CSF) based peripheral blood stem cells (PBSCs) transplantation or just a porous tantalum rod implantation. Safety and efficacy of the combination treatment were assessed over 36 months via hip function, convers...
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