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500mg dose of Vitamin C effective in preventing complex regional pain syndrome
August 2013
500mg dose of Vitamin C effective in preventing complex regional pain syndrome
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:1
Can Vitamin C Prevent Complex Regional Pain Syndrome in Patients with Wrist Fractures?: A Randomized, Controlled, Multicenter Dose-Response Study
J Bone Joint Surg Am. 2007 Jul;89(7):1424-31Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
416 patients with wrist fracture (427 fractures) were randomized to receive treatment of Vitamin C (either 200, 500 or 1500mg daily) or a placebo. The results indicated that the use of Vitamin C with a daily dose of 500mg for 50 days after a wrist fracture, was the most successful in preventing the development of complex regional pain syndrome.
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