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Local antibiotics added to routine regimen limits infection after IM for tibia fracture
July 2014
Local antibiotics added to routine regimen limits infection after IM for tibia fracture
Study Type:Meta-analysis/Systematic Review
OE Level Evidence:2
Journal Level of Evidence:3
Systematic review and meta-analysis of the additional benefit of local prophylactic antibiotic therapy for infection rates in open tibia fractures treated with intramedullary nailing
Int Orthop. 2014 May;38(5):1025-30Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Evidence from 21 studies (14 Retrospective or Case Studies; 6 RCTs; 1 Review) was identified using two distinct searches to evaluate the addition of locally-delivered antibiotics to prophylactic administration of systemic antibiotics in order to further limit incidence of infection of tibial fractures fixed intramedullary nailing. The evidence presented in this systematic review and meta-analysis ...
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