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AAOS: Fondaparinux appears to be associated with elevated blood coagulation factors

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Ace Report Cover
March 2014

AAOS: Fondaparinux appears to be associated with elevated blood coagulation factors

Vol: 3| Issue: 3| Number:48| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Thrombogenicity and Platelet Function in Lower Extremity Total Joint Arthroplasty: A Prospective Randomized Study

Contributing Authors:
B Kapadia MJ McElroy K Bliden MG Gesheff CJ Franzese S Banerjee US Tantry P Gurbel MA Mont

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

51 patients undergoing elective total knee and hip arthroplasty were randomized to receive thromboprophylaxis with either subcutaneous injection of fondaparinux (2.5 mg) or aspirin (325 mg) plus compression stockings. The purpose of this study was to determine whether changes in thrombogenicity can be measured with blood coagulation factors and platelet counts. Analysis of blood drawn on postopera...

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