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Intra-articular bone marrow-derived stem cell injection effective in high tibial osteotomy
April 2014
Intra-articular bone marrow-derived stem cell injection effective in high tibial osteotomy
Study Type:Randomized Trial
OE Level Evidence:2
Journal Level of Evidence:2
Injectable cultured bone marrow-derived mesenchymal stem cells in varus knees with cartilage defects undergoing high tibial osteotomy: a prospective, randomized controlled clinical trial with 2 years
Arthroscopy. 2013 Dec;29(12):2020-8. doi: 10.1016/j.arthro.2013.09.074Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
56 patients with medial compartmental osteoarthritis and genu varum were randomized to undergo a high tibial osteotomy with or without an intra-articular injection of cultured autologous bone marrow-derived mesenchymal stem cells (MSC), administered 3 weeks post-treatment. The purpose of this study was to evaluate the clinical outcomes and MRI results of both the cell-recipient and control groups ...
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