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Zoledronic Acid increased hip BMD in acute Charcot neuroarthropathy

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Ace Report Cover
September 2013

Zoledronic Acid increased hip BMD in acute Charcot neuroarthropathy

Vol: 2| Issue: 8| Number:11| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Effect of immobilization, off-loading and zoledronic acid on bone mineral density in patients with acute Charcot neuroarthropathy: A prospective randomized trial

Foot Ankle Surg. 2013 Jun;19(2):121-4. doi: 10.1016/j.fas.2012.12.007. Epub 2013 Feb 20

Contributing Authors:
H Maenpaa TK Pakarinen HJ Laine M Kahonen P Mattila J Lahtela

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Synopsis

35 patients, suffering from acute midfoot Charcot neuropathy (CNA), were randomized to study the effects of zoledronic acid and immobilization on Bone Mineral Density (BMD) changes in lumbar spine and both hips. Patients were assigned to either receive zoledronic acid or a placebo treatment. 6 month results demonstrated a rise in hip BMD in zoledronic acid-treated group, and a fall in affected and...

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