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Extended prophylaxis with semuloparin reduces VTE after hip fracture surgery
June 2013
Extended prophylaxis with semuloparin reduces VTE after hip fracture surgery
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Extended venous thromboembolism prophylaxis in patients undergoing hip fracture surgery - the SAVE-HIP3 study
Bone Joint J. 2013 Apr 1;95-B(4):459-66. doi: 10.1302/0301-620X.95B4.30730Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
OE EXCLUSIVE
Dr. Fisher discusses extended venous thromboembolism prophylaxis in patients undergoing hip fracture surgery
Synopsis
Following a 7-10 day open label run-in phase which studied the safety and efficacy of prophylaxis with semuloparin, 469 patients were randomized in a 2:1 ratio to a 19-23-day long treatment of either semuloparin or a placebo in a double blind phase. 23 days after the end of treatment, the semuloparin group had a 79% relative risk reduction in the rate of any venous thromboembolism or all-cause dea...
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