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Annual infusion of zoledronic acid reduces days of back pain, disability, and bed rest
March 2014
Annual infusion of zoledronic acid reduces days of back pain, disability, and bed rest
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Once-yearly zoledronic acid and days of disability, bed rest, and back pain: randomized, controlled HORIZON Pivotal Fracture Trial
J Bone Miner Res. 2011 May;26(5):984-92. doi: 10.1002/jbmr.292Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
In a secondary prespecified analysis, 7736 postmenopausal women with osteoporosis were examined to evaluate the effect of once-yearly zoledronic acid on improving back pain and disability. Patients received either a single 15 minute intravenous fusion of zoledronic acid (5 mg) or placebo at baseline, 12 months, and 24 months. The assessment at 36 months indicated that zoledronic acid significantly...
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