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TKA: Epoetin alfa leads to improved hematological parameters and lower risk of transfusion
August 2013
TKA: Epoetin alfa leads to improved hematological parameters and lower risk of transfusion
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Preoperative Epoetin Alfa vs Autologous Blood Donation in Primary Total Knee Arthroplasty
J Arthroplasty. 2006 Aug;21(5):628-35Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
50 patients with pretreatment hemoglobin level of 100 to 130 g/L who were undergoing primary total knee reconstruction were randomized to receive standard care using preoperative autologous blood donation (PAD) or recombinant human erythropoietin (epoetin alfa) at 40 000 U (preoperative day 14). Blood counts were done every day for up to 5 days after the operation. From the day of surgery to two d...
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